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Fırat University Journal of Health Sciences (Veterinary)
2018, Cilt 32, Sayı 1, Sayfa(lar) 001-005
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Radiological Comparison of Effects of Bioactive Glass, Mineralized and Demineralized Bone Matrix on Bone Healing
1Bağlar İlçe Gıda, Tarım ve Hayvancılık Müdürlüğü, Diyarbakır, TÜRKİYE
2Fırat Üniversitesi, Veteriner Fakültesi, Cerrahi Anabilim Dalı, Elazığ, TÜRKİYE
Keywords: Bone healing, graft, bioactive glass, mineralized bone matrix, demineralized bone matrix

In this study, it was aimed to compare the radiological findings of the effects of bioactive glass, mineralized bone matrix (MBM), and demineralized bone matrix (DBM) on healing of experimental bone defects in rabbits.

Fourteen, 4-5-months old, male New Zealand rabbits were used in the study. The rabbits were randomly divided into 2 main groups for 30 and 60 day follow-ups and each group contained 7 randomly selected rabbits. Under general anesthesia, a total of four defects, two on the proximal metaphysis of both tibia of each rabbits were created. Fourteen of 56 bone defects created were left empty to serve as the control group. The other defects were filled with bioactive glass, MBM and DBM (n=14 in each group). Thus, all graft groups were formed in each rabbit.

Radiological examinations were performed immediately after the operation, and on 15th, 30th, 45th, and 60th days. As a result of the radiological examinations, bone healing in the bioactive glass group was determined to be better than the other groups.

As a result, bioactive glass was observed to significantly increase the early term bone healing, which suggest that it can safely be used as a good graft. It is considered that the results of the study will contribute to patient welfare by providing better healing in a short time and facilitating the choosing of the graft material in clinical cases where the use of bone graft is necessary.

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