[ Ana Sayfa | Editörler | Danışma Kurulu | Dergi Hakkında | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | E-Posta ]
Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi
2000, Cilt 14, Sayı 2, Sayfa(lar) 291-294
[ Turkish ] [ PDF ]
The Relation Between C-Reactive Protein (C-RP) And Coronary Artery Lesion In Patients With Unstabil Angina Pectoris
Fırat Üniversitesi Tıp Fakültesi, Elazığ-TÜRKİYE
Keywords: C-reactive protein, Unstable angina pectoris, Coronary heart disease

The prognosis of unstable angina pectoris in patients with high levels of C-RP is poor. In this study we aimed to determine, the relation between C-RP levels and number of affected coronary arteries and their localisation which are detected by angiography and cardiac troponin T level and the frequency of cardiac events.

A total of 57 male patients with refractory unstable angina pectoris patients with an mean age of 59±1 years and with symptom duration time of 4.5±1 hours were included in the study. None of the patients had myocardial infarction (MI), travmatic injury, inflamation or tumoral events which can affect the acute phase reactans. In the first 48 hours serial ECG and cardiac enzymes were measured at 6 hour intervals. The cases were divided into two groups according to their basal C-RP levels as Group-I (C-RP>5 mg/dl) and Group-II (C-RP≤5 mg/dl). After 72 hours, angiography was performed in all patients. Coronary artery lesion, localisation and the number of affected vessel, cardiac troponin T level and cardiac event number were determined. Except recurrent symptoms, MI and cardiac death were not observed in all subjects.

There was no significant difference between the groups regarding to their age, sex, symptom duration time, affected coronary artery lesion localisation, proximal lesion and risk factors (p>0.05). In Group-I, the number of affected lesions and cardiac troponin T positivity and frequency of cardiac events were significantly higher than in Group-II (p<0.05)

In conclusion, high levels of C-RP, an acute phase reactent, in patients with unstable angina pectoris was in close relation with the number of affected vessels, cardiac troponin T positivity and recurrent symptoms.

[ Turkish ] [ PDF ]
[ Ana Sayfa | Editörler | Danışma Kurulu | Dergi Hakkında | İçindekiler | Arşiv | Yayın Arama | Yazarlara Bilgi | E-Posta ]