In this study, a decision support system is designed which makes things easier for physicians and helps them for recognizing various diseases from histopathologic images. In automatic enumeration of cell system, the desired applications, which necessitate more attention and long time for physician, are carried out at short time and high success rates. The developed system composed of a segmentation stage which discriminates the desired cells from the background, an enhancement stage which improves the representation of the image and an enumeration stage which counts the cells from the histopathologic image. The evaluation of the proposed system is done on the histopathologic images which were taken from the hepatitis and cancer patients. The system results are compared with the physician results and it is seen that both results are matched at 90 % high accuracy rate.