To report two cases of pseudohypopyon that occurred during intravitreal triamcinolone injection.

In the same operating day, a 58-year-old man with left phakic eye and 52-year-old man with right pseudophakic eye underwent intravitreal triamcinolone injection (0.1 ml). In both patients, pseudohypopyon developed during intravitreal triamcinolone injection.

Pseudohypopyon resolved without specific treatment.

Pseudohypopyon seems to be a distinct clinical entity after intravitreal triamcinolone injection. If progressive intraocular inflammation and ocular discomfort do not occur, close observational management is indicated.