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Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi
2020, Cilt 34, Sayı 1, Sayfa(lar) 061-067
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Systemic Inflammatory Response Syndrome and Sepsis
Muhammed Sertaç EROĞLU1, Akın KIRBAŞ2
1Atatürk Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Erzurum, TÜRKİYE
2Bozok Üniversitesi, Veteriner Fakültesi, İç Hastalıkları Anabilim Dalı, Yozgat, TÜRKİYE
Keywords: SIRS, sepsis, inflammation, diagnosis, prognosis, treatment

Systemic inflammatory response syndrome (SIRS) is the set of events that the body gives hematologic and immunologic responses due to microbial contaminated and decontaminated reasons. It is sepsis that SIRS and infection co-exist. Infectious and non-infectious causes are important in etiology. Hyperemia and petechial bleeding foci, prolongation of capillary filling time, the presence of a distinctive dark toxic line on the gums is common clinical signs. These clinical symptoms include dynamic or non-dynamic response index. Hematologically, leukocytosis/leukopenia, neutrophilia/neutropenia, lymphopenia, anemia, and thrombocytopenia are important results. Hyperglycemia or hypoglycemia, hypoalbuminemia, and hyperbilirubinemia are common findings in the biochemical profile. For diagnosis clinical findings, anamnesis, serum biochemical parameters, serum bioindicators, and hemogram findings should be evaluated together. When evaluating prognosis in SIRS and sepsis, the effective response to daily treatment should be interpreted. In treatment, diet, antibiotics, immunotherapy, fluid and electrolyte applications, and symptomatic and supportive treatments are important.

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