Boron is an important mineral found in nature as compounds, and plays roles in various biological processes, and is an essential trace element required for the growth of humans and animals. Turkey ranks first with a 73% share of total boron reserves in the world. Boron enters the body through respiration, digestion, and skin, and affects energy, mineral, and bone metabolism in humans and animals. Some studies show that boron compounds have bacteriostatic, bactericidal, fungistatic, fungicidal, and antiviral effects against bacteria, mold, yeast, and viruses. Boric acid and sodium tetraborate are used as preservatives in foods (sturgeon eggs) and food supplements, and studies are carried out for their use in food packaging materials. This paper reviews the effects of boron on human and animal health, antimicrobial properties, and their potential for use in foods.