Recently, a total of three feline hemotropic Mycoplasma sp., (Mycoplasma haemofelis, ‘‘Candidatus Mycoplasma haemominutum'' and ‘Candidatus Mycoplasma turicensis') in cats with anemia have been recognized. Healthy cats with “Candidatus Mycoplasma haemominutum” infection may prone to a life-threatening anemia with accompanying concurrent disease or immune suppression, such as in the case reported here. The present article describes the presence of ‘'Candidatus Mycoplasma haemominutum'' infection (diagnosed by polymerase chain reaction) resulted in fatality in a Siamese crossbred cat in Antalya.