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Fırat Üniversitesi Sağlık Bilimleri Tıp Dergisi |
2017, Cilt 31, Sayı 3, Sayfa(lar) 137-141 |
[ Turkish ] [ Tam Metin ] [ PDF ] |
Relation of Platelet to Lymphocyte Ratio withTheSeverity of Acute Pancreatitis |
Yasemin KAYA1, Harun DÜĞEROĞLU1, Hamza ÇINAR2 |
1Ordu Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Ordu,TÜRKİYE 2Ordu Üniversitesi, Tıp Fakültesi, Genel Cerrahi Anabilim Dalı, Ordu, TÜRKİYE |
Keywords: Acute pancreatitis, Ranson criteria, platelet lymphocyte ratio |
Objective: In this study we aimed to investigate the relationship of the platelet to lymphocyte ratio (PLR) which is a marker associated with systemic inflammation and the ranson criteria which indicates these verity of acute pancreatitis on admission.
Materials and Methods: Data according to patients diagnosed as biliary and non- biliary acute pancreatitis at the emergency department in the last five years have been reviewed. A total of 418 cases (301 biliary, 117 non- biliary) were included to the study. Hemogram and biochemical parameters, ages, sex, and length of stay were recorded at the time of initial application. Patients were classified 2 groups depending on RansonCriteria (Biliarypancreatitis: age>70 years, white blood cell (WBC) >18000 /mm3, glucose>220 mg/dL, lactate dehydrogenase (LDH) >400 U/L, aspartate aminotransferase (AST)>250 U/L non-biliarypancreatitis: age>55 years, WBC>16000 /mm3, glucose>200 mg/dL, LDH>350 U/L, AST>250 U/L) whether score<3 or score≥ 3. Results: There were significant correlation between platelet lymphocyte ratio (PLR) and AST, LDH and WBC (respectively; r=0.17 P<0.001; r=0.18 P<0.001; r=0.10 P=0.01). We found that the uric acid, albumin, neutrophil lymphocyte ratio and PLR were independent predictors of acute pancreatitis severity as result of the linear regression analysis. Conclusion: PLR which features systemic inflammation may be used as a simple and reliable indicator to determine acute pancreatitis severity. |
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