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Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi
2001, Cilt 15, Sayı 1, Sayfa(lar) 113-120
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Investigations on Serum Vitamin C Levels in Some Infectious Diseases of Cattles
Mustafa İSSİ, Yusuf GÜL
Fırat Üniversitesi Veteriner Fakültesi, Elazığ-TÜRKİYE
Keywords: Ascorbic acid, cattle, theileriosis, malignant catarrhal fever, foot and mouth disease.

This study was aimed to determine if there is a need of using ascorbic acid in the medical treatment of Theileriosis, Malignant Catarrhal Fever and Foot and Mouth Disease by measuring the vitamin C levels and to find out the relation between the lack of vitamin C and patachie and echymose hemorrhages were investigated.

A total of 80 cows allocating 20 healthy cows (Control group) and 60 sick cows (20 cows with Theileriosis (Th group), 20 cows with Malignant Catarrhal Fever (MCF group), 20 cows with Foot and Mouth Diesase (FMD group)) were used. All the animals used in the study were systematically and clinically examined and blood samples were obtained from animals for the laboratory analysis.

In the laboratory analysis; red and white blood cell counts were detected using Thoma microslides, packed cell volume were measured by microhematocrit metod, hemoglobin value by Sahli metod, thrombocyte counts by Coulter Max M brand Cell Counter, bleeding time by Duke metod, coagulation time by microslides metod. Partial thromboplastin time were determined by detecting clotin time after addition of CaCl3 and cephalin to plasma. Serum vitamin C levels were measured by phosphotungustic acid metod in Schimadzu UV – 1208, UV – VIS Spectrophotometer.

Serum vitamin C levels in control, Th, MCF and FMD groups were found to be 0.60 mg / dl, 0.43 mg / dl, 0.42 mg / dl and 0.40 mg / dl, respectively.

As a result, because of the low serum vitamin C levels of the animals in Th, MCF and FMD groups, administration of vitamin C was suggested to be useful with classical treatment. Although it is thought that the administration of vitamin C can decrease the tendency of bleeding and hemorrhages, it is necessary to carry out more comprehensive studies.

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