Maternal circulation and calf circulation are separated from each other since the type of ruminant placenta is syndesmochorial. Therefore, newborn calves need the immunity compounds from the colostrum of their mothers in the first 28 days after birth, which is also called neonatal period. The amount of Immunoglobulin G, which constitutes 85-90% of the total immunoglobulin, plays a significant role in determining the quality in the colostrum for an effective passive immune transfer. The aim of this study was to compare the colostrum quality of Native Black breed cattle, which is one of our native gene sources, and Brown Swiss cattle, which is a combined milk-oriented culture breed. The animal material of the study consisted of 23 pure Native Black cattle and 43 pure Brown Swiss cattle. ELISA method was used to determine the colostrum immunoglobulin G level. According to the descriptive statistical data of Native Black and Brown Swiss cattle, mean Immunoglobulin G concentrations were found as 133.1±77.28 mg/mL and 74.60±28.44 mg/mL, respectively. Immunoglobulin G data between the two groups were found to be statistically significant when compared with the independent t-test. (P<0.001). In conclusion, this study revealed that the colostrum quality of our Native Black breed was significantly higher than that of the Brown Swiss breed, which has a higher milk yield.